By Forbes J. Burkowski
The fantastic thing about Protein buildings and the math at the back of Structural Bioinformatics
Providing the framework for a one-semester undergraduate direction, Structural Bioinformatics: An Algorithmic Approach indicates how one can follow key algorithms to resolve difficulties with regards to macromolecular structure.
Helps scholars cross extra of their learn of Structural Biology
Following a few introductory fabric within the first few chapters, the textual content solves the longest universal subsequence challenge utilizing dynamic programming and explains the technology types for the Nussinov and MFOLD algorithms. It then stories series alignment, besides the fundamental mathematical calculations wanted for measuring the geometric houses of macromolecules. After how coordinate modifications facilitate the interpretation and rotation of molecules in a 3D house, the writer introduces structural comparability strategies, superposition algorithms, and algorithms that evaluate relationships inside a protein. the ultimate bankruptcy explores how regression and type have gotten extra helpful in protein research and drug design.
At the Crossroads of Biology, arithmetic, and desktop Science
Connecting biology, arithmetic, and computing device technology, this useful textual content provides quite a few bioinformatics issues and difficulties inside of a systematic technique that emphasizes nature (the resource of empirical observations), technological know-how (the mathematical modeling of the common process), and computation (the technological know-how of calculating predictions and mathematical items according to mathematical models).
Read Online or Download Structural Bioinformatics: An Algorithmic Approach (Chapman & Hall/CRC Mathematical and Computational Biology) PDF
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